I've tried quite a few brands and lines over the years but keep coming back to D'addario for their feel and tone. I find the EXL range gives a nice, harmonically bright tone while the newer NYXL range are fuller and purer but have less high frequency harmonics and so are great for taming and giving more richness and body to bright guitars or pickups (e.g. they sound great on my ESP Eclipse with Bare Knuckle "Mule" pickups).